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Extending Admixture Mapping to Nuclear Pedigrees: Application to Sarcoidosis

We describe statistical methods that extend the application of admixture mapping from unrelated individuals to nuclear pedigrees, allowing existing pedigree-based collections to be fully exploited. Computational challenges have been overcome by developing a fast algorithm that exploits the factorial...

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Détails bibliographiques
Auteurs principaux: McKeigue, Paul M., Colombo, Marco, Agakov, Felix, Datta, Indrani, Levin, Albert, Favro, David, Gray-Montgomery, Courtney, Iannuzzi, Michael C., Rybicki, Benjamin A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756835/
https://ncbi.nlm.nih.gov/pubmed/23371909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21710
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