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Malaria Parasite Type 4 Equilibrative Nucleoside Transporters (ENT4) are Purine Transporters with Distinct Substrate Specificity*

Malaria, caused by Plasmodia parasites, affects hundreds of millions of people. As purine auxotrophs, Plasmodia use transporters to import host purines for subsequent metabolism by the purine salvage pathway. Thus, purine transporters are attractive drug targets. All sequenced Plasmodia genomes enco...

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Hlavní autoři: Frame, I. J., Merino, Emilio F., Schramm, Vern L., Cassera, María B., Akabas, Myles H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756485/
https://ncbi.nlm.nih.gov/pubmed/22670848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20112220
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