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Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells

[Image: see text] The misfolding and aggregation of amyloid-β (Aβ) peptides into amyloid fibrils is regarded as one of the causative events in the pathogenesis of Alzheimer’s disease (AD). Tanshinones extracted from Chinese herb Danshen (Salvia Miltiorrhiza Bunge) were traditionally used as anti-inf...

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Detalhes bibliográficos
Main Authors: Wang, Qiuming, Yu, Xiang, Patal, Kunal, Hu, Rundong, Chuang, Steven, Zhang, Ge, Zheng, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756451/
https://ncbi.nlm.nih.gov/pubmed/23506133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400051e
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