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Cytomegalovirus-based based cancer vaccines expressing TRP2 induce rejection of melanoma in mice

Cytomegalovirus (CMV) induces strong and long-lasting immune responses, which make it an attractive candidate for a cancer vaccine vector. In this study, we tested whether a tumor antigen expressed in CMV can induce a strong anti-tumor effect. We expressed an unmodified melanoma antigen, mouse tyros...

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Autors principals: Xu, Guangwu, Smith, Tameka, Grey, Finn, Hill, Ann B.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756148/
https://ncbi.nlm.nih.gov/pubmed/23811402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.06.068
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