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Competition for antigen at the level of the antigen presenting cell is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection

Cytomegalovirus’s (CMV’s) unique ability to drive the expansion of virus-specific T-cell populations over the course of a lifelong, persistent infection has generated interest in the virus as a potential vaccine strategy. When designing CMV-based vaccine vectors to direct immune responses against HI...

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Detalhes bibliográficos
Main Authors: Farrington, Lila A., Smith, Tameka A., Grey, Finn, Hill, Ann B., Snyder, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608834/
https://ncbi.nlm.nih.gov/pubmed/23455500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203151
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