Cardiomyocyte Protection by GATA-4 Gene Engineered Mesenchymal Stem Cells Is Partially Mediated by Translocation of miR-221 in Microvesicles

INTRODUCTION: microRNAs (miRs), a novel class of small non-coding RNAs, are involved in cell proliferation, differentiation, development, and death. In this study, we found that miR-221 translocation by microvesicles (MVs) plays an important role in cardioprotection mediated by GATA-4 overexpressed...

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Detalhes bibliográficos
Main Authors: Yu, Bin, Gong, Min, Wang, Yigang, Millard, Ronald W., Pasha, Zeeshan, Yang, Yueting, Ashraf, Muhammad, Xu, Meifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756018/
https://ncbi.nlm.nih.gov/pubmed/24015301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073304
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