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GATA-4 promotes myocardial transdifferentiation of mesenchymal stromal cells via up-regulating IGFBP-4

BACKGROUND AIMS: GATA-4 is a cardiac transcription factor and plays an important role in cell lineage differentiation during development. We investigated whether overexpression of GATA-4 increases adult mesenchymal stromal cell (MSC) transdifferentiation into a cardiac phenotype in vitro. METHODS: M...

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Hlavní autoři: LI, HONGXIA, ZUO, SHI, PASHA, ZEESHAN, YU, BIN, HE, ZHISONG, WANG, YIGANG, YANG, XIANGJUN, ASHRAF, MUHAMMAD, XU, MEIFENG
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366502/
https://ncbi.nlm.nih.gov/pubmed/21846294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2011.597380
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