Clusterin/Akt Up-Regulation Is Critical for GATA-4 Mediated Cytoprotection of Mesenchymal Stem Cells against Ischemia Injury

BACKGROUND: Clusterin (Clu) is a stress-responding protein with multiple biological functions. Our preliminary microarray studies show that clusterin was prominently upregulated in mesenchymal stem cells (MSCs) overexpressing GATA-4 (MSC(GATA-4)). We hypothesized that the upregulation of clusterin i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Bin, Yang, Yueting, Liu, Huan, Gong, Min, Millard, Ronald W., Wang, Yi-Gang, Ashraf, Muhammad, Xu, Meifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786134/
https://ncbi.nlm.nih.gov/pubmed/26962868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151542
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