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Anthrax Edema Factor Toxicity Is Strongly Mediated by the N-end Rule
Anthrax edema factor (EF) is a calmodulin-dependent adenylate cyclase that converts adenosine triphosphate (ATP) into 3’–5’-cyclic adenosine monophosphate (cAMP), contributing to the establishment of Bacillus anthracis infections and the resulting pathophysiology. We show that EF adenylate cyclase t...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755998/ https://ncbi.nlm.nih.gov/pubmed/24015319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074474 |
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