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Mitochondrial DNA with a Large-Scale Deletion Causes Two Distinct Mitochondrial Disease Phenotypes in Mice

Studies in patients have suggested that the clinical phenotypes of some mitochondrial diseases might transit from one disease to another (e.g., Pearson syndrome [PS] to Kearns-Sayre syndrome) in single individuals carrying mitochondrial (mt) DNA with a common deletion (∆mtDNA), but there is no direc...

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Bibliografiske detaljer
Main Authors: Katada, Shun, Mito, Takayuki, Ogasawara, Emi, Hayashi, Jun-Ichi, Nakada, Kazuto
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755915/
https://ncbi.nlm.nih.gov/pubmed/23853091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.007245
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