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Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene
We generated transmitochondrial mice (mito-mice) that carry a mutation in the tRNA(Lys) gene encoded by mtDNA for use in studies of its pathogenesis and transmission profiles. Because patients with mitochondrial diseases frequently carry mutations in the mitochondrial tRNA(Lys) and tRNA(Leu(UUR)) ge...
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| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939884/ https://ncbi.nlm.nih.gov/pubmed/24510903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318109111 |
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