A Small Molecule Modulates Circadian Rhythms through Phosphorylation of the Period Protein

TIME SHIFT: A high-throughput cell-based screen identified a benzothiazole analogue, LH846, which induces period lengthening of the circadian rhythm. Affinity chromatography coupled with mass spectrometry and genomic analysis identified protein kinase CKIδ as the biological target of LH846 (see pict...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Lee, Jae Wook, Hirota, Tsuyoshi, Peters, Eric C., Garcia, Michael, Gonzalez, Rodolfo, Cho, Charles Y., Wu, Xu, Schultz, Peter G., Kay, Steve A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755734/
https://ncbi.nlm.nih.gov/pubmed/21954091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201103915
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller