Prefrontal Cortex HCN1 Channels Enable Intrinsic Persistent Neural Firing and Executive Memory Function

In many cortical neurons, HCN1 channels are the major contributors to I(h), the hyperpolarization-activated current, which regulates the intrinsic properties of neurons and shapes their integration of synaptic inputs, paces rhythmic activity, and regulates synaptic plasticity. Here, we examine the p...

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Autori principali: Thuault, Sébastien J., Malleret, Gaël, Constantinople, Christine M., Nicholls, Russell, Chen, Irene, Zhu, Judy, Panteleyev, Andrey, Vronskaya, Svetlana, Nolan, Matthew F., Bruno, Randy, Siegelbaum, Steven A., Kandel, Eric R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755709/
https://ncbi.nlm.nih.gov/pubmed/23966682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2427-12.2013
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