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Externally Sensitized Deprotection of PPG-Masked Carbonyls as a Spatial Proximity Probe in Photoamplified Detection of Binding Events

Externally-sensitized electron-transfer fragmentation in dithiane PPG-protected carbonyls is adopted for detection and amplification of molecular recognition events. The new methodology allows for detection of as low as 50 attomoles of avidin utilizing an imager based on a low sensitivity mass-produ...

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Autors principals: Gustafson, Tiffany P., Metzel, Greg A., Kutateladze, Andrei G.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755620/
https://ncbi.nlm.nih.gov/pubmed/22252455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2pp05326h
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