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West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

West Nile virus (WNV) encephalitis is characterized by neuroinflammation, neuronal loss and blood–brain barrier (BBB) disruption. However, the mechanisms associated with the BBB disruption are unclear. Complex interactions between the tight junction proteins (TJP) and the adherens junction proteins...

詳細記述

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書誌詳細
主要な著者: Roe, Kelsey, Kumar, Mukesh, Lum, Stephanie, Orillo, Beverly, Nerurkar, Vivek R., Verma, Saguna
フォーマット: Artigo
言語:Inglês
出版事項: Society for General Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755517/
https://ncbi.nlm.nih.gov/pubmed/22398316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.040899-0
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