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West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

West Nile virus (WNV) encephalitis is characterized by neuroinflammation, neuronal loss and blood–brain barrier (BBB) disruption. However, the mechanisms associated with the BBB disruption are unclear. Complex interactions between the tight junction proteins (TJP) and the adherens junction proteins...

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Detalhes bibliográficos
Main Authors: Roe, Kelsey, Kumar, Mukesh, Lum, Stephanie, Orillo, Beverly, Nerurkar, Vivek R., Verma, Saguna
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755517/
https://ncbi.nlm.nih.gov/pubmed/22398316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.040899-0
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