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Reversal of West Nile virus-induced blood-brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor

Though compromised blood-brain barrier (BBB) is a pathological hallmark of WNV- associated neurological sequelae, underlying mechanisms are unclear. We characterized the expression of matrix metalloproteinases (MMP) in WNV-infected human brain-microvascular endothelial cells (HBMVE) and -cortical as...

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Detalhes bibliográficos
Main Authors: Verma, Saguna, Kumar, Mukesh, Gurjav, Ulziijargal, Lum, Stephanie, Nerurkar, Vivek R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102050/
https://ncbi.nlm.nih.gov/pubmed/19922973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.10.036
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