Φορτώνει......
Transactivation of Gene Expression by NFκB is Dependent on Thioredoxin Reductase Activity
The redox-sensitive transcription factor NFκB mediates the expression of genes involved in inflammation and cell survival. Thioredoxin reductase-1 (TR1) and its substrate thioredoxin-1 (Trx1) act together to reduce oxidized cysteine residues within the DNA binding domain of NFκB and promote maximal...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755477/ https://ncbi.nlm.nih.gov/pubmed/21782934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.06.028 |
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