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Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes

The real-time measurement of biomass has been addressed since many years. The quantification of biomass in the induction phase of a recombinant bioprocess is not straight forward, since biological burden, caused by protein expression, can have a significant impact on the cell morphology and physiolo...

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Autori principali: Wechselberger, Patrick, Sagmeister, Patrick, Herwig, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755222/
https://ncbi.nlm.nih.gov/pubmed/23178981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-012-0848-4
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