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Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes
The real-time measurement of biomass has been addressed since many years. The quantification of biomass in the induction phase of a recombinant bioprocess is not straight forward, since biological burden, caused by protein expression, can have a significant impact on the cell morphology and physiolo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755222/ https://ncbi.nlm.nih.gov/pubmed/23178981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-012-0848-4 |
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