Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma

BACKGROUND: The growth and recurrence of several cancers appear to be driven by a population of cancer stem cells (CSCs). Glioblastoma, the most common primary brain tumor, is invariably fatal, with a median survival of approximately 1 year. Although experimental data have suggested the importance o...

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Autori principali: Vik-Mo, Einar Osland, Nyakas, Marta, Mikkelsen, Birthe Viftrup, Moe, Morten Carstens, Due-Tønnesen, Paulina, Suso, Else Marit Inderberg, Sæbøe-Larssen, Stein, Sandberg, Cecilie, Brinchmann, Jan E., Helseth, Eirik, Rasmussen, Anne-Marie, Lote, Knut, Aamdal, Steinar, Gaudernack, Gustav, Kvalheim, Gunnar, Langmoen, Iver A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755221/
https://ncbi.nlm.nih.gov/pubmed/23817721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1453-3
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