Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine

Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells. Moreover, IDO expression promotes resistance to immunotherapies targeting immune checkpoints such as the cytotoxic T lymphocyte antigen-4 (CTL...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Case Rep Med
Main Authors: Sioud, Mouldy, Nyakas, Marta, Sæbøe-Larssen, Stein, Mobergslien, Anne, Aamdal, Steinar, Kvalheim, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967686/
https://ncbi.nlm.nih.gov/pubmed/27504122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9639585
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados