Effect of Stearic Acid on Enalapril Stability and Dissolution from Multiparticulate Solid Dosage Forms

Enalapril maleate (EM) is a widely used anti-hypertensive drug which is unstable when mixed with excipients. Enalaprilate and diketopiperazine (DPK) are the main degradation products of enalapril. The in situ preparation of enalapril sodium salt (NaE) has been used to improve drug stability in dosag...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Cunha, Talita A., Serpa, Raphael C., de Oliveira, Ana Paula M., Nasser, Letícia N., de Freitas, Luis Alexandre P., Taveira, Stephania F., Diniz, Danielle G. A., Lima, Eliana M., Marreto, Ricardo N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755139/
https://ncbi.nlm.nih.gov/pubmed/23897034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0006-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky