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The Role of Functional Excipients in Solid Oral Dosage Forms to Overcome Poor Drug Dissolution and Bioavailability

Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds is usually very low as a result of their poor solubility properties. In order...

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書目詳細資料
發表在:Pharmaceutics
Main Authors: van der Merwe, Jannes, Steenekamp, Jan, Steyn, Dewald, Hamman, Josias
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284856/
https://ncbi.nlm.nih.gov/pubmed/32344802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12050393
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