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Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration

It is now well established that tumor cell invasion through tissue is strongly regulated by the microstructural and mechanical properties of the extracellular matrix (ECM). However, it remains unclear how these physical microenvironmental inputs are jointly processed with oncogenic lesions to drive...

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Autors principals: Pathak, Amit, Kumar, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755126/
https://ncbi.nlm.nih.gov/pubmed/23832051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ib40017d
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