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Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration

It is now well established that tumor cell invasion through tissue is strongly regulated by the microstructural and mechanical properties of the extracellular matrix (ECM). However, it remains unclear how these physical microenvironmental inputs are jointly processed with oncogenic lesions to drive...

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Detalhes bibliográficos
Main Authors: Pathak, Amit, Kumar, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755126/
https://ncbi.nlm.nih.gov/pubmed/23832051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ib40017d
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