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CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity

Dysregulation of cell cycle genes such as Cyclin D1 and Chk1 contributes to the undifferentiated phenotype of neuroblastoma (NB). CASZ1 functions as a tumor suppressor in NB; here we sought to determine how loss of CASZ1 contributes to cell cycle dysregulation in NB. CASZ1 restoration in NB cells de...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Zhihui, Rader, JulieAnn, He, Stanley, Phung, Tanya, Thiele, Carol J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755071/
https://ncbi.nlm.nih.gov/pubmed/23892435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25265
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