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Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes

Cellular senescence is a stable cell cycle arrest that can be induced by stresses such as telomere shortening, oncogene activation or DNA damage. Senescence is a potent anticancer barrier that needs to be circumvented during tumorigenesis. The cell cycle regulator p16(INK4a) is a key effector upregu...

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Bibliografski detalji
Glavni autori: Martin, Nadine, Raguz, Selina, Dharmalingam, Gopuraja, Gil, Jesús
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755069/
https://ncbi.nlm.nih.gov/pubmed/24067365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25331
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