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Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes
Cellular senescence is a stable cell cycle arrest that can be induced by stresses such as telomere shortening, oncogene activation or DNA damage. Senescence is a potent anticancer barrier that needs to be circumvented during tumorigenesis. The cell cycle regulator p16(INK4a) is a key effector upregu...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755069/ https://ncbi.nlm.nih.gov/pubmed/24067365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25331 |
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