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Poor Metabolizers at the Cytochrome P450 2C19 Loci Is at Increased Risk of Developing Cancer in Asian Populations

BACKGROUND: CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes, which play a central role in activating and detoxifying many carcinogens and endogenous compounds thought to be involved in the development of cancer. In the past decade, two common polymorphisms among CYP2C19 (CYP2C...

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Detalhes bibliográficos
Main Authors: Wang, Hong, Song, Kang, Chen, Zenggan, Yu, Yanmin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754911/
https://ncbi.nlm.nih.gov/pubmed/24015291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073126
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