Peroxynitrite-Mediated Oxidative Modifications of Complex II: Relevance in the Myocardial Infarction()

Increased O(2)(•−) and NO production is a key mechanism of mitochondrial dysfunction in myocardial ischemia/reperfusion injury. In complex II, oxidative impairment and enhanced tyrosine nitration of the 70 kDa FAD-binding protein occurs in the post-ischemic myocardium, and is thought to be mediated...

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Autori principali: Zhang, Liwen, Chen, Chwen-Lih, Kang, Patrick T., Garg, Vivek, Hu, Keli, Green-Church, Kari B., Chen, Yeong-Renn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754874/
https://ncbi.nlm.nih.gov/pubmed/20143804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9018237
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