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Mass Spectrometry Profiles Superoxide-Induced Intra-molecular Disulfide in the FMN-binding Subunit of Mitochondrial Complex I

Protein thiols with regulatory functions play a critical role in maintaining the homeostasis of the redox state in mitochondria. One major host of regulatory cysteines in mitochondria is complex I, with the thiols primarily located on its 51 kDa FMN-binding subunit. In response to oxidative stress,...

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Detalhes bibliográficos
Main Authors: Zhang, Liwen, Xu, Hua, Chen, Chwen-Lih, Green-Church, Kari B., Freitas, Michael A., Chen, Yeong-Renn
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614441/
https://ncbi.nlm.nih.gov/pubmed/18789718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2008.08.004
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