The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2

Osteoblasts are responsible for the formation and mineralization of the skeleton. To identify novel regulators of osteoblast differentiation, we conducted an unbiased forward genetic screen using a lentiviral-based shRNA library. This functional genomics analysis led to the identification of the mic...

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Main Authors: Zou, Weiguo, Greenblatt, Matthew B., Brady, Nicholas, Lotinun, Sutada, Zhai, Bo, de Rivera, Heather, Singh, Anju, Sun, Jun, Gygi, Steven P., Baron, Roland, Glimcher, Laurie H., Jones, Dallas C.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754873/
https://ncbi.nlm.nih.gov/pubmed/23918955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111790
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