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Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk

Wolff’s law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling. However, how the mechanostat influences bone remodeling remains...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Wang, Lijun, You, Xiuling, Lotinun, Sutada, Zhang, Lingli, Wu, Nan, Zou, Weiguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962448/
https://ncbi.nlm.nih.gov/pubmed/31941964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14146-6
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