Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

Trials to test new drugs currently in development against tuberculosis in humans are impractical. All animal models to prioritize new regimens are imperfect, but nonhuman primates (NHPs) infected with Mycobacterium tuberculosis develop active tuberculosis (TB) disease with a full spectrum of lesion...

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Detalhes bibliográficos
Main Authors: Lin, Philana Ling, Coleman, Teresa, Carney, Jonathan P. J., Lopresti, Brian J., Tomko, Jaime, Fillmore, Dan, Dartois, Veronique, Scanga, Charles, Frye, L. James, Janssen, Christopher, Klein, Edwin, Barry, Clifton E., Flynn, JoAnne L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754323/
https://ncbi.nlm.nih.gov/pubmed/23796926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00277-13
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