Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

Trials to test new drugs currently in development against tuberculosis in humans are impractical. All animal models to prioritize new regimens are imperfect, but nonhuman primates (NHPs) infected with Mycobacterium tuberculosis develop active tuberculosis (TB) disease with a full spectrum of lesion...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Philana Ling, Coleman, Teresa, Carney, Jonathan P. J., Lopresti, Brian J., Tomko, Jaime, Fillmore, Dan, Dartois, Veronique, Scanga, Charles, Frye, L. James, Janssen, Christopher, Klein, Edwin, Barry, Clifton E., Flynn, JoAnne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754323/
https://ncbi.nlm.nih.gov/pubmed/23796926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00277-13
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