Involvement of the Reparative DNA Polymerase Pol X of African Swine Fever Virus in the Maintenance of Viral Genome Stability In Vivo

The function of the African swine fever virus (ASFV) reparative DNA polymerase, Pol X, was investigated in the context of virus infection. Pol X is a late structural protein that localizes at cytoplasmic viral factories during DNA replication. Using an ASFV deletion mutant lacking the Pol X gene, we...

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Bibliographic Details
Main Authors: Redrejo-Rodríguez, Modesto, Rodríguez, Javier M., Suárez, Cristina, Salas, José, Salas, María L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754141/
https://ncbi.nlm.nih.gov/pubmed/23824796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01173-13
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