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Identification of a Suppressor Mutation That Improves the Yields of Hexon-Modified Adenovirus Vectors
We have generated hexon-modified adenovirus serotype 5 (Ad5) vectors that are not neutralized by Ad5-specific neutralizing antibodies in mice. These vectors are attractive for the advancement of vaccine products because of their potential for inducing robust antigen-specific immune responses in peop...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754123/ https://ncbi.nlm.nih.gov/pubmed/23824800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00462-13 |
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