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Immunological and Virological Analyses of Rhesus Macaques Immunized with Chimpanzee Adenoviruses Expressing the Simian Immunodeficiency Virus Gag/Tat Fusion Protein and Challenged Intrarectally with Repeated Low Doses of SIVmac

Human adenovirus (AdHu)-based candidate AIDS vaccine can provide protection from simian immunodeficiency virus (SIV) transmission and disease progression. However, their potential use may be limited by widespread preexisting immunity to the vector. In contrast, preexisting immunity to chimpanzee ade...

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Bibliografiska uppgifter
Huvudupphovsmän: Cervasi, Barbara, Carnathan, Diane G., Sheehan, Katherine M., Micci, Luca, Paiardini, Mirko, Kurupati, Raj, Tuyishime, Steven, Zhou, Xiang Yang, Else, James G., Ratcliffe, Sarah J., Ertl, Hildegund C. J., Silvestri, Guido
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754116/
https://ncbi.nlm.nih.gov/pubmed/23804645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01456-13
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