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Activated CD4(+)CCR5(+) T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques
An effective T-cell–based AIDS vaccine should induce strong HIV-specific CD8(+) T cells in mucosal tissues without increasing the availability of target cells for the virus. Here, we evaluated five immunization strategies that include Human adenovirus-5 (AdHu5), Chimpanzee adenovirus-6 (AdC6) or -7...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4299179/ https://ncbi.nlm.nih.gov/pubmed/25550504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407466112 |
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