Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development

A novel human Middle East respiratory syndrome coronavirus (MERS-CoV) caused outbreaks of severe acute respiratory syndrome (SARS)-like illness with a high mortality rate, raising concerns of its pandemic potential. Dipeptidyl peptidase-4 (DPP4) was recently identified as its receptor. Here we showe...

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Detalhes bibliográficos
Main Authors: Du, Lanying, Zhao, Guangyu, Kou, Zhihua, Ma, Cuiqing, Sun, Shihui, Poon, Vincent K. M., Lu, Lu, Wang, Lili, Debnath, Asim K., Zheng, Bo-Jian, Zhou, Yusen, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754113/
https://ncbi.nlm.nih.gov/pubmed/23824801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01048-13
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