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Myeloblastic Cell Lines Mimic Some but Not All Aspects of Human Cytomegalovirus Experimental Latency Defined in Primary CD34(+) Cell Populations

Human cytomegalovirus (HCMV) is a significant human pathogen that achieves lifelong persistence by establishing latent infections in undifferentiated cells of the myeloid lineage, such as CD34(+) hematopoietic progenitor cells. When latency is established, viral lytic gene expression is silenced in...

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Hlavní autoři: Albright, Emily R., Kalejta, Robert F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754112/
https://ncbi.nlm.nih.gov/pubmed/23824798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01436-13
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