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Myeloblastic Cell Lines Mimic Some but Not All Aspects of Human Cytomegalovirus Experimental Latency Defined in Primary CD34(+) Cell Populations

Human cytomegalovirus (HCMV) is a significant human pathogen that achieves lifelong persistence by establishing latent infections in undifferentiated cells of the myeloid lineage, such as CD34(+) hematopoietic progenitor cells. When latency is established, viral lytic gene expression is silenced in...

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Главные авторы: Albright, Emily R., Kalejta, Robert F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754112/
https://ncbi.nlm.nih.gov/pubmed/23824798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01436-13
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