CD34(+) Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence

In human cytomegalovirus (HCMV)-seropositive patients, CD34(+) hematopoietic progenitor cells (HPCs) provide an important source of latent virus that reactivates following cellular differentiation into tissue macrophages. Multiple groups have used primary CD34(+) HPCs to investigate mechanisms of vi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Crawford, Lindsey B., Hancock, Meaghan H., Struthers, Hillary M., Streblow, Daniel N., Yurochko, Andrew D., Caposio, Patrizia, Goodrum, Felicia D., Nelson, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925096/
https://ncbi.nlm.nih.gov/pubmed/33177198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02105-20
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