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Cell Line Models for Human Cytomegalovirus Latency Faithfully Mimic Viral Entry by Macropinocytosis and Endocytosis

Human cytomegalovirus (HCMV) enters primary CD34(+) hematopoietic progenitor cells by macropinocytosis, where it establishes latency in part because its tegument-transactivating protein, pp71, remains associated with endosomes and is therefore unable to initiate productive, lytic replication. Here w...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Lee, Jeong-Hee, Pasquarella, Joseph R., Kalejta, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803280/
https://ncbi.nlm.nih.gov/pubmed/31391271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01021-19
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