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Latent HIV-1 Can Be Reactivated by Cellular Superinfection in a Tat-Dependent Manner, Which Can Lead to the Emergence of Multidrug-Resistant Recombinant Viruses
The HIV-1 latent reservoir represents an important source of genetic diversity that could contribute to viral evolution and multidrug resistance following latent virus reactivation. This could occur by superinfection of a latently infected cell. We asked whether latent viruses might be reactivated w...
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Autors principals: | , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Microbiology
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754111/ https://ncbi.nlm.nih.gov/pubmed/23804632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01165-13 |
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