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The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency

The establishment of HIV-1 latency can result from limiting levels of transcription initiation or elongation factors, restrictive chromatin modifications, transcriptional interference, and insufficient Tat activity. Since the viral protein Tat can counteract many of these factors, we hypothesized th...

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Main Authors: Donahue, Daniel A., Kuhl, Björn D., Sloan, Richard D., Wainberg, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302319/
https://ncbi.nlm.nih.gov/pubmed/22238306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06648-11
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