Quantitative Comparison of Human Parainfluenza Virus Hemagglutinin-Neuraminidase Receptor Binding and Receptor Cleavage

The human parainfluenza virus (hPIV) hemagglutinin-neuraminidase (HN) protein binds (H) oligosaccharide receptors that contain N-acetylneuraminic acid (Neu5Ac) and cleaves (N) Neu5Ac from these oligosaccharides. In order to determine if one of HN′s two functions is predominant, we measured the affin...

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Main Authors: Tappert, Mary M., Porterfield, J. Zachary, Mehta-D'Souza, Padmaja, Gulati, Shelly, Air, Gillian M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754076/
https://ncbi.nlm.nih.gov/pubmed/23740997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00739-13
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