Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus

The overall CD8 T cell response to human/simian immunodeficiency virus (HIV/SIV) targets a collection of discrete epitope specificities. Some of these epitope-specific CD8 T cells emerge in the weeks and months following infection and rapidly select for sequence variants, whereas other CD8 T cell re...

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Autori principali: Harris, Max, Burns, Charles M., Becker, Ericka A., Braasch, Andrew T., Gostick, Emma, Johnson, Randall C., Broman, Karl W., Price, David A., Friedrich, Thomas C., O'Connor, Shelby L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754066/
https://ncbi.nlm.nih.gov/pubmed/23785211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00909-13
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