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Human Cytomegalovirus Interleukin-10 Polarizes Monocytes toward a Deactivated M2c Phenotype To Repress Host Immune Responses

Several human cytomegalovirus (HCMV) genes encode products that modulate cellular functions in a manner likely to enhance viral pathogenesis. This includes UL111A, which encodes homologs of human interleukin-10 (hIL-10). Depending upon signals received, monocytes and macrophages become polarized to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Avdic, Selmir, Cao, John Z., McSharry, Brian P., Clancy, Leighton E., Brown, Rebecca, Steain, Megan, Gottlieb, David J., Abendroth, Allison, Slobedman, Barry
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754025/
https://ncbi.nlm.nih.gov/pubmed/23864618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00912-13
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