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The Role of E3 in pH Protection during Alphavirus Assembly and Exit

Alphaviruses are small enveloped viruses whose surface is covered by spikes composed of trimers of E2/E1 glycoprotein heterodimers. During virus entry, the E2/E1 dimer dissociates within the acidic endosomal environment, freeing the E1 protein to mediate fusion of the viral and endosome membranes. E...

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Bibliografiska uppgifter
Huvudupphovsmän: Uchime, Onyinyechukwu, Fields, Whitney, Kielian, Margaret
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754015/
https://ncbi.nlm.nih.gov/pubmed/23864626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01507-13
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