Functional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir Resistance

The influenza virus neuraminidase H274Y substitution is a highly prevalent amino acid substitution associated with resistance to the most heavily used influenza drug, oseltamivir. Previous structural studies suggest that the group specific 252 residue (Y252 in group 1 and T252 in group 2) might be a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, Qing, Qi, Jianxun, Wu, Yan, Kiyota, Hiromasa, Tanaka, Kosuke, Suhara, Yoshitomo, Ohrui, Hiroshi, Suzuki, Yasuo, Vavricka, Christopher J., Gao, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753999/
https://ncbi.nlm.nih.gov/pubmed/23824808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01129-13
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados